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Use of neostigmine in capecitabine-induced paralytic ileus

Abstract

Paralytic ileus is a recognised side effect of the oral agent capecitabine. We present this report on a patient with metastatic colorectal cancer who was treated with capecitabine and presented with persistent paralytic ileus which did not respond to standard conservative measures. Neostigmine was administered safely, resulting in resolution of the paralytic ileus. This approach merits further investigation.

Tumori 2013; 99(5): e225 - e228

Article Type: CASE REPORT

DOI:10.1700/1377.15320

Authors

Gabriel Mak, Robyn Ward, Yahya Shehabi, Ramya Venkateswaran, Melvin Chin

Article History

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Authors

  • Mak, Gabriel [PubMed] [Google Scholar]
    Prince of Wales Clinical School, Faculty of Medicine, University of NSW, Sydney, Australia
  • Ward, Robyn [PubMed] [Google Scholar]
    Prince of Wales Clinical School, Faculty of Medicine, University of NSW, Sydney, Australia
  • Shehabi, Yahya [PubMed] [Google Scholar]
    Prince of Wales Clinical School, Faculty of Medicine, University of NSW, Sydney, Australia
  • Venkateswaran, Ramya [PubMed] [Google Scholar]
    Prince of Wales Clinical School, Faculty of Medicine, University of NSW, Sydney, Australia
  • Chin, Melvin [PubMed] [Google Scholar]
    Prince of Wales Clinical School, Faculty of Medicine, University of NSW, Sydney, Australia

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