Use of 18F-choline positron emission tomography/CT in high-risk prostate cancer: a case of solitary adrenal metastasis


Computed tomography and magnetic resonance imaging detected an isolated adrenal lesion in an elderly man with high-risk prostate cancer who was undergoing radiotherapy (RT) and hormonal therapy (HT). When prostate-specific antigen (PSA) was 31.66 ng/mL, the lesion was not identified as a metastasis by 18F-choline positron emission tomography/computed tomography (18F-choline-PET/CT). When PSA was over 100 ng/mL, 18F-choline-PET/CT diagnosed the malignancy. After adrenalectomy, PSA returned to normal, and stable disease remission was obtained. This case suggests that atypical metastasis may be underdiagnosed.

Tumori 2015; 101(1): e21 - e23

Article Type: CASE REPORT



Fabio Matrone, Silvio Sivolella, Rita Bellavita, Luciano Casciola, Enrico Giuseppe Cristallini, Cynthia Aristei

Article History


Financial support: No financial support was received for this sub­mission.
Conflict of interest: The authors have no conflict of interest.

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  • Radiation Oncology Section, University of Perugia, Perugia - Italy
  • Nuclear Medicine and PET Centre, San Giovanni Battista Hospital, Foligno - Italy
  • Radiation Oncology Division, Perugia General Hospital, Perugia - Italy
  • Department of Surgery, Division of General, Minimally Invasive and Robotic Surgery, San Matteo Hospital, Spoleto - Italy
  • Division of Pathological Anatomy, San Giovanni Battista Hospital, Foligno - Italy
  • Radiation Oncology Section, University of Perugia and Perugia General Hospital, Perugia - Italy

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