To investigate the role of 3D ultrasound (3D-US) in target volume delineation in prostate cancer radiotherapy.
Four patients with intermediate risk prostate cancer and metal artifacts on planning computed tomography (CT) due to previous bilateral hip replacement underwent 3D-US with the Clarity platform (Clarity System, Elekta, Stockholm, Sweden) to allow for image-guided procedures. Ultrasound and CT images were coregistered to allow for better delineation of the prostate gland and organs at risk (OAR). Electron density override (EDO) and standard electron density (EDS) methods were compared for appropriate dose calculation.
3D-US and planning CT minimized image artifacts, providing better evidence of patient anatomy, particularly regarding soft tissue visualization. Prostate gland and seminal vesicles were better delineated, particularly in the posterior aspect. Anterior rectal wall and bladder neck were more visible. No difference was found in terms of average planning target volume dose, D15%, or D25% for rectum or D15%, D25%, or D35% of bladder between EDO and EDS.
3D-US proved to be a viable tool for target volume and OAR visualization in patients with prostate cancer with hip prostheses.
Tumori 2015; 101(5): e133 - e137
Article Type: SHORT COMMUNICATION
AuthorsFrancesca Arcadipane, Christian Fiandra, Pierfrancesco Franco, Fernando Munoz, Paolo Irgolini, Elisabetta Trino, Mario Levis, Alessia Guarneri, Umberto Ricardi
- • Accepted on 09/03/2015
- • Available online on 13/05/2015
- • Published online on 09/09/2015
This article is available as full text PDF.
- Arcadipane, Francesca [PubMed] [Google Scholar] 1
- Fiandra, Christian [PubMed] [Google Scholar] 1
- Franco, Pierfrancesco [PubMed] [Google Scholar] 1, * Corresponding Author (firstname.lastname@example.org)
- Munoz, Fernando [PubMed] [Google Scholar] 2
- Irgolini, Paolo [PubMed] [Google Scholar] 2
- Trino, Elisabetta [PubMed] [Google Scholar] 1
- Levis, Mario [PubMed] [Google Scholar] 1
- Guarneri, Alessia [PubMed] [Google Scholar] 2
- Ricardi, Umberto [PubMed] [Google Scholar] 1
Department of Oncology, Radiation Oncology, University of Turin, Turin - Italy
Radiotherapy Department, AOU Città della Salute e della Scienza, Turin - Italy