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Reduction of risk of dying from tobacco-related diseases after quitting smoking in Italy

Abstract

Aims and background

The aims of this paper are to compute the risks of dying of ischemic heart disease (IHD), lung cancer (LC), stroke, and chronic obstructive pulmonary disease (COPD) for Italian smokers by gender, age and daily number of cigarettes smoked, and to estimate the benefit of stopping smoking in terms of risk reduction.

Methods

Life tables by sex and smoking status were computed for each smoking-related disease based on Italian smoking data, and risk charts with 10-year probabilities of death were computed for never, current and former smokers.

Results

Men aged 45-49 years, current smokers, have a 8, 10, 3 and 1 in 1,000 chance of dying of IHD, LC, stroke and COPD, respectively, whereas women with the same characteristics have a 2, 6, 3 and 1 in 1,000 chance, respectively, for all smokers combined, i.e., independent of the smoking intensity. The risk reduction rates from quitting smoking are remarkable: a man who quits smoking at 45-49 years can reduce the risk of dying of IHD, LC, stroke and COPD in the next 10 years by 43%, 53%, 57% and 55%, respectively; a woman by 49%, 49%, 59% and 57%, respectively.

Conclusions

Estimates of risk reduction by quitting smoking are useful to provide a sounder scientific basis for public health messages and clinical advice.

Tumori 2015; 101(6): 657 - 663

Article Type: ORIGINAL RESEARCH ARTICLE

DOI:10.5301/tj.5000307

Authors

Giulia Carreras, Francesco Pistelli, Franco Falcone, Laura Carrozzi, Andrea Martini, Giovanni Viegi, Giuseppe Gorini

Article History

Disclosures

Financial support: This work was published with the contribution of the Istituto Toscano Tumori (ITT), grant proposal 2008.
Conflict of interest: The authors have no conflict of interest to declare.

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Authors

Affiliations

  • Unit of Environmental & Occupational Epidemiology, Cancer Prevention & Research Institute (ISPO), Florence - Italy
  • Pulmonary Unit, Cardiothoracic and Vascular Department, University Hospital of Pisa, Cisanello (Pisa) - Italy
  • Unit of Pulmonary Environmental Epidemiology, Institute of Clinical Physiology, Italian National Research Council (IFC-CNR), Pisa - Italy
  • Italian Association of Hospital Pulmonologists (AIPO) Research, Milan - Italy
  • Institute of Biomedicine and Molecular Immunology, Italian National Research Council (IBIM-CNR), Palermo - Italy

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