Radiosurgical options in neuro-oncology: a review on current tenets and future opportunities. Part II: adjuvant radiobiological tools


Stereotactic radiosurgery (SRS) is currently a well-established, minimally invasive treatment for many primary and secondary tumors, especially deep-sited lesions for which traditional neurosurgical procedures were poorly satisfactory or not effective at all. The initial evolution of SRS was cautious, relying on more than 30 years of experimental and clinical work that preceded its introduction into the worldwide medical community. This path enabled a brilliant present, and the continuous pace of technological advancement holds promise for a brighter future. Part II of this review article will cover the impact of multimodal adjuvant technologies on SRS, and their input to the crucial role played by neurosurgeons, radiation oncologists and medical physicists in the management and care of fragile neuro-oncological patients.

Tumori 2015; 101(1): 57 - 63




Mario Ganau, Roberto Israel Foroni, Massimo Gerosa, Giuseppe Kenneth Ricciardi, Michele Longhi, Antonio Nicolato

Article History


Financial support: Research Grant by Fondazione Benefica Kathleen Foreman Casali.
Conflict of interest: The authors do not report any financial, personal or professional conflict of interest concerning the materials and methods used in this study or the findings specified in this paper.

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  • Department of Neuroscience, University Hospital, AOUI, Verona - Italy
  • Department of Biomedical Engineering, University of Cagliari, Cagliari - Italy
  • Department of Pathology and Diagnosis, University Hospital, AOUI, Verona - Italy

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