Male breast cancer: clinical features and multimodal treatment in a retrospective survey analysis at Italian centers


Aims and background. We report a collection of data about early breast cancer in male patients from 13 Italian institutions.
Methods and study design. We obtained data from patient charts and performed statistical analysis. The primary end points were overall survival and disease-free survival.
Results. A total of 205 men with invasive breast cancer was identified, with a median age of 66 years. Pathological characteristics were heterogeneous for T stage, N stage and HER2 status. Histological subtype was predominantly ductal infiltrating carcinoma. Most of them were hormone receptor positive. Mastectomy was the most common strategy. Postsurgical treatment was not standardized. Patients with large tumors were more likely to be treated with chemotherapy. Disease recurrence was associated with an ER+ and PR+ status.
Conclusions. We identified a correlation between relapse and hormone receptor expression, as is the case in female breast cancer.

Tumori 2013; 99(5): 596 - 600




Nicla La Verde, Elena Collovà, Sara Lonardi, Daniele Generali, Anna Moretti, Francesco Atzori, Marina Cazzaniga, Chiara Saggia, Luca Tondulli, Ilaria Marcon, Anna Lisa Gentile, Rosalba Rossello, Olga Martelli, Stefania Aglione, Gabriella Farina, Michela Cinquini, Marina Garassino

Article History

This article is available as full text PDF.

  • If you are a Subscriber, please log in now.

  • Article price: Eur 36,00
  • You will be granted access to the article for 72 hours and you will be able to download any format (PDF or ePUB). The article will be available in your login area under "My PayPerView". You will need to register a new account (unless you already own an account with this journal), and you will be guided through our online shop. Online purchases are paid by Credit Card through PayPal.
  • If you are not a Subscriber you may:
  • Subscribe to this journal
  • Unlimited access to all our archives, 24 hour a day, every day of the week.


  • La Verde, Nicla [PubMed] [Google Scholar]
    AO Fatebenefratelli e Oftalmico, Department of Oncology, Milan, Italy
  • Collovà, Elena [PubMed] [Google Scholar]
    Hospital of Legnano, Division of Medical Oncology, Legnano, Italy
  • Lonardi, Sara [PubMed] [Google Scholar]
    Veneto Oncology Institute IRCCS, Medical Oncology Unit 1, Padua, Italy
  • Generali, Daniele [PubMed] [Google Scholar]
    Azienda Istituti Ospitalieri di Cremona, UO Multidisciplinare di Patologia Mammaria, Cremona, Italy
  • Moretti, Anna [PubMed] [Google Scholar]
    AO Fatebenefratelli e Oftalmico, Department of Oncology, Milan, Italy
  • Atzori, Francesco [PubMed] [Google Scholar]
    AO Universitaria di Cagliari, Medical Oncology Unit, Cagliari, Italy
  • Cazzaniga, Marina [PubMed] [Google Scholar]
    San Gerardo Hospital, Department of Medical Oncology, Monza, Italy
  • Saggia, Chiara [PubMed] [Google Scholar]
    Maggiore Hospital, Department of Oncology, Novara, Italy
  • Tondulli, Luca [PubMed] [Google Scholar]
    AO Universitaria Integrata di Verona Borgo Trento Hospital, Department of Oncology, Verona, Italy
  • Marcon, Ilaria [PubMed] [Google Scholar]
    Ospedale di Circolo e Fondazione Macchi, Department of Oncology, Varese, Italy
  • Gentile, Anna Lisa [PubMed] [Google Scholar]
    ”G Mazzini” Hospital, Medical Oncology Unit, Teramo, Italy
  • Rossello, Rosalba [PubMed] [Google Scholar]
    Policlinico Universitario “G Martino”, Department of Human Pathology, Medical Oncology and Integrated Therapies Unit, Messina, Italy
  • Martelli, Olga [PubMed] [Google Scholar]
    AO S Giovanni-Addolorata, Medical Oncology Unit, Rome, Italy
  • Aglione, Stefania [PubMed] [Google Scholar]
    AO Desio e Vimercate, Department of Oncology, Vimercate (MI), Italy
  • Farina, Gabriella [PubMed] [Google Scholar]
    AO Fatebenefratelli e Oftalmico, Department of Oncology, Milan, Italy
  • Cinquini, Michela [PubMed] [Google Scholar]
    Mario Negri Institute for Pharmacological Research, Department of Oncology, Milan, Italy
  • Garassino, Marina [PubMed] [Google Scholar]
    Fondazione IRCCS Istituto Nazionale dei Tumori, Medical Oncology Unit 1, Milan, Italy

Article usage statistics

The blue line displays unique views in the time frame indicated.
The yellow line displays unique downloads.
Views and downloads are counted only once per session.

No supplementary material is available for this article.