Inferior mesenteric artery chemoembolization and chemotherapy for advanced rectal cancer: report of a clinical case


Patients with advanced and incurable colorectal cancer have a very poor prognosis. Curative-intent resection was performed in 70%-90% of cases in reported series of colorectal cancer, sometimes after neoadjuvant chemotherapy and radiotherapy. The remaining 10%-30% of patients are treated with palliative intent, where treatment is aimed at relieving disease-related symptoms and improving quality of life. The provision of palliative care for these patients is complicated and outcomes are often disappointing. Although there are many available options including a variety of surgical and nonsurgical interventions, the best management remains controversial. Transarterial chemoembolization with irinotecan-loaded drug-eluting beads (DEBIRI) is an effective, minimally invasive procedure performed by interventional radiologists that allows intra-arterial drug delivery to stop vascular feeding and exert local cytotoxic effects. We here report on a patient treated with DEBIRI followed by systemic chemotherapy with the FOLFOX regimen for locally advanced, inoperable colorectal cancer.

Tumori 2015; 101(3): e82 - e84

Article Type: CASE REPORT



Roberto Bini, Simone Comelli, Alfredo Addeo, Tiziana Viora, Federica Vana, Giacomo Paolo Vaudano, Daniele Savio, Renzo Leli

Article History


Financial support: None.
Conflict of interest: None.

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  • General Surgery Department, SG Bosco Hospital ASL To2, Turin - Italy
  • Interventional Radiology/Neuroradiology, SG Bosco Hospital ASL To2, Turin - Italy
  • Lincoln County Hospital, Lincoln - UK
  • Oncology Department, SG Bosco Hospital, Turin - Italy

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