Hemolytic uremic syndrome induced by infusion of oxaliplatin: a case report


Introduction. Oxaliplatin is a third-generation platinum compound with proven antitumor activity in the treatment of colorectal cancer. The occurrence of life-threating hemolitic uremic syndrome has been observed after oxaliplatin therapy. The kind of tumor and treatmentmodalities seemto influence the onset of hemolitic uremic syndrome.
Methods. The clinical course of the case is reviewed and compared with reports of other similar cases in the literature.
Results. We describe the development of hemolitic uremic syndrome as a result of prolonged oxaliplatin treatment of a colon cancer patient.
Conclusions. Although this rare event requires the concurrence of other unknown factors, it should be considered in a decision-making setting.

Tumori 2011; 97(5): e31 - e33

Article Type: CASE REPORT



Patrizia Racca, Rosella Spadi, Gianluca Fora, Laura Fanchini, Giuliana Ritorto, Laura Ferrari, Francesco Pinta, Patrizia List, Libero Ciuffreda

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