Giant cemento-ossifying fibroma of the maxilla



Fibro-osseous lesions of the skull and facial bones are benign tumors, but they can be mistaken for malignant tumors due to their clinically aggressive behavior. Cemento-ossifying fibroma (COF) is a benign fibro-osseous lesion characterized by slow growth and fibrous and calcified tissue content. COFs are locally destructive lesions causing deformities in the bones. The recurrence risk is high if they are not completely removed.

Case report

In this case report we describe a giant COF mimicking chondrosarcoma in the oral cavity of a 55-year-old woman causing significant facial deformity and feeding problems.


Giant COF occurs rarely in the jaws and given that this lesion has similar imaging and clinical features to several other tumors, the diagnosis is always a challenge for clinicians, radiologists and pathologists.

Tumori 2015; 101(6): e163 - e166

Article Type: CASE REPORT



Adnan Unal, Nurcan Yurtsever Kum, Rauf Oguzhan Kum, Aysun Erdogan, Deniz Sozmen Ciliz, Servet Guresci, Muge Ozcan

Article History


Financial support: None.
Conflict of interest: None declared.

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  • Department of Otorhinolaryngology, Hitit University, Çorum - Turkey
  • ENT Clinic, Ankara Numune Education and Research Hospital, Ankara - Turkey
  • Radiology Clinic, Ankara Numune Education and Research Hospital, Ankara - Turkey
  • Pathology Clinic, Ankara Numune Education and Research Hospital, Ankara - Turkey

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