Advertisement

Comparison of different predictive tools of axillary status in breast cancer with micrometastatic sentinel node

Abstract

Aim. To compare the performance of six different nomograms and one score in the prediction of non-sentinel lymph node status in a subset of women with breast cancer and micrometastatic sentinel nodes (SN).
Material and methods. Twenty-five patients were included in the study. Five different nomograms not specifically designed for micrometastatic SN, one recently published nomogram specially developed for this type of patients and one score were analyzed, and the corresponding receiver operating characteristic curves were obtained. The area under the curve (AUC) was calculated, as well as the false negative and false positive results and their corresponding rates (FNR and FPR) for a cutoff of ≤10% or ≤4 points.
Results. The Memorial Sloan Kettering Cancer Center (MSKCC) nomogram showed the best performance in this low-risk group of patients (AUC 0.900, FPR 64%, FNR 0%), followed by the French nomogram.
Conclusions. The MSKCC nomogram seems to have the highest accuracy in the identification of patients with low risk of further axillary disease in the subgroup of women with micrometastatic SN.

Tumori 2014; 100(4): 415 - 419

Article Type: ORIGINAL RESEARCH ARTICLE

DOI:10.1700/1636.17898

Authors

José Manuel Cordero García, Azahara Palomar Muñoz, Ana María García Vicente, Germán Andrés Jiménez Londoño, Antonio Alberto León Martín, Ricardo Pardo García, Ángel Soriano Castrejón

Article History

This article is available as full text PDF.

  • If you are a Subscriber, please log in now.

  • Article price: Eur 36,00
  • You will be granted access to the article for 72 hours and you will be able to download any format (PDF or ePUB). The article will be available in your login area under "My PayPerView". You will need to register a new account (unless you already own an account with this journal), and you will be guided through our online shop. Online purchases are paid by Credit Card through PayPal.
  • If you are not a Subscriber you may:
  • Subscribe to this journal
  • Unlimited access to all our archives, 24 hour a day, every day of the week.

Authors

  • García, José Manuel Cordero [PubMed] [Google Scholar]
    Department of Nuclear Medicine, Hospital General Universitario, Ciudad Real, Spain
  • Muñoz, Azahara Palomar [PubMed] [Google Scholar]
    Department of Nuclear Medicine, Hospital General Universitario, Ciudad Real, Spain
  • Vicente, Ana María García [PubMed] [Google Scholar]
    Department of Nuclear Medicine, Hospital General Universitario, Ciudad Real, Spain
  • Londoño, Germán Andrés Jiménez [PubMed] [Google Scholar]
    Department of Nuclear Medicine, Hospital General Universitario, Ciudad Real, Spain
  • León Martín, Antonio Alberto [PubMed] [Google Scholar]
    Investigation Unit, Hospital General Universitario, Ciudad Real, Spain
  • García, Ricardo Pardo [PubMed] [Google Scholar]
    Department of Surgery, Hospital General Universitario, Ciudad Real, Spain
  • Castrejón, Ángel Soriano [PubMed] [Google Scholar]
    Department of Nuclear Medicine, Hospital General Universitario, Ciudad Real, Spain

Article usage statistics

The blue line displays unique views in the time frame indicated.
The yellow line displays unique downloads.
Views and downloads are counted only once per session.

No supplementary material is available for this article.