Advertisement

Role of radiotherapy in the treatment of renal cell cancer: updated and critical review

Abstract

Purpose

The growing incidence of renal cell carcinoma (RCC) raises many questions about the management of these patients. The late clinical presentation, the presence of locally advanced or metastatic disease at diagnosis, the difficulty of radical surgical excision, and radioresistance make it one of the more challenging tumors to treat. The primary objective of this article is to propose an updated and critical review of the role of radiotherapy (RT) in the treatment of RCC.

Methods

This literature review is based on data from meta-analyses and randomized, prospective, and retrospective studies. We collected reports from 1970 to the present about preoperative RT, postoperative RT, stereotactic body RT, radiosurgery, and intraoperative RT in locally advanced renal cancer and in metastatic diseases.

Results

We emphasize the progress made in RT technology that allowed the creation of a more personalized and focused treatment with a minimum rate of complications.

Conclusions

In the coming years, new studies will be published to confirm and increase the indications for use of RT.

Tumori 2017; 103(6): 504 - 510

Article Type: REVIEW

DOI:10.5301/tj.5000640

Authors

Vincenzo Fusco, Salvatore Parisi, Barbara d’Andrea, Michele Troiano, Maria Antonietta Clemente, Franco Morelli, Rocchina Caivano, Giuseppe Guglielmi

Article History

Disclosures

Financial support: No financial support was received for this submission.
Conflict of interest statement: None of the authors has conflict of interest with this submission.

This article is available as full text PDF.

  • If you are a Subscriber, please log in now.

  • Article price: Eur 36,00
  • You will be granted access to the article for 72 hours and you will be able to download any format (PDF or ePUB). The article will be available in your login area under "My PayPerView". You will need to register a new account (unless you already own an account with this journal), and you will be guided through our online shop. Online purchases are paid by Credit Card through PayPal.
  • If you are not a Subscriber you may:
  • Subscribe to this journal
  • Unlimited access to all our archives, 24 hour a day, every day of the week.

Authors

Affiliations

  • Unit of Radiation Oncology, IRCCS “CROB” Rionero in Vulture, Potenza - Italy
  • Unit of Radiation Therapy, IRCCS “Casa Sollievo della Sofferenza” San Giovanni Rotondo, Foggia - Italy
  • Unit of Radiology, University of Foggia, Foggia - Italy
  • Unit of Oncology, IRCCS “Casa Sollievo della Sofferenza” San Giovanni Rotondo, Foggia - Italy
  • Unit of Radiology, IRCCS “Casa Sollievo della Sofferenza” San Giovanni Rotondo, Foggia - Italy

Article usage statistics

The blue line displays unique views in the time frame indicated.
The yellow line displays unique downloads.
Views and downloads are counted only once per session.

No supplementary material is available for this article.