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Bladder cancer diagnosis: the role of CT urography

Abstract

Aims and Background

To evaluate the diagnostic performance of computed tomography urography (CTU), we first compared it with cystoscopy and subsequently analyzed which CTU phase of acquisition has the highest diagnostic accuracy in identifying bladder cancer.

Methods

In 2013, 177 patients underwent both cystoscopy and CTU. For all acquisition phases, we calculated sensitivity, specificity, diagnostic accuracy, and positive and negative predictive value (PPV and NPV, respectively). We also evaluated the Cohen κ coefficient.

Results

Computed tomography urography sensitivity, specificity, diagnostic accuracy, PPV, and NPV were as follows: 96.3%, 86.4%, 92.8%, 92.9%, and 92.7%; concordance calculated with Cohen κ was good: 0.8413. The arterial acquisition phase showed the highest diagnostic accuracy, identifying 93.4% of all lesions.

Conclusions

Computed tomography urography is an accurate examination for the diagnosis of bladder cancer, and the arterial acquisition phase provides the best diagnostic information.

Tumori 2015; 101(4): 412 - 417

Article Type: ORIGINAL RESEARCH ARTICLE

DOI:10.5301/tj.5000331

Authors

Emanuela Capalbo, Anna Kluzer, Michela Peli, Maria Cosentino, Elisabetta Berti, Maurizio Cariati

Article History

Disclosures

Financial support: None.
Conflict of interest: None.

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Authors

Affiliations

  • School of Specialization of Diagnostic and Interventional Radiology, University of Milan, Milan - Italy
  • Department of Diagnostic Sciences, Division of Radiology and Interventional Radiology, San Carlo Borromeo Hospital, Milan - Italy
  • Department of Diagnostic Sciences, Division of Pathologist, San Carlo Borromeo Hospital, Milan - Italy

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