Bilateral breast radiation delivered with static angle tomotherapy (TomoDirect): clinical feasibility and dosimetric results of a single patient


We herein report on a case of synchronous bilateral breast cancer patient undergoing adjuvant intensity-modulated whole breast with static angle tomotherapy (TomoDirect). The patient was treated with a hypofractionated schedule employing a simultaneous integrated boost approach. Radiotherapy schedule was 45 Gy/20 fractions (2.25 Gy daily) to the bilateral whole breast and 50 Gy/20 fractions (2.5 Gy daily) to the 2 lumpectomy cavities. Treatment was delivered over 4 weeks. Dosimetric results were robust with consistent target coverage and adequate normal tissue avoidance. Treatment was generally well-tolerated and acute toxicity profile was mild. The present report highlights the promising clinical feasibility of TomoDirect for bilateral breast irradiation.

Tumori 2015; 101(1): e4 - e8

Article Type: CASE REPORT



Pierfrancesco Franco, Fernanda Migliaccio, Paolo Torielli, Piera Sciacero, Giuseppe Girelli, Domenico Cante, Cecilia Arrichiello, Valeria Casanova Borca, Andrea Peruzzo Cornetto, Gianmauro Numico, Maria Rosa La Porta, Santi Tofani, Umberto Ricardi

Article History


Financial support: No financial support was received for this submission.
Conflict of interest: The authors have no conflict of interest.

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  • Radiation Oncology Department, Tomotherapy Unit, Ospedale Regionale ‘U. Parini’, AUSL Valle d’Aosta, Aosta - Italy
  • Medical Physics Department, Ospedale Regionale ‘U. Parini’, AUSL Valle d’Aosta, Aosta - Italy
  • Medical Oncology Department, Ospedale Regionale ‘U. Parini’, AUSL Valle d’Aosta, Aosta - Italy
  • Department of Oncology, Radiation Oncology, University of Torino, Turin - Italy

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