Amphicrine carcinoma is a peculiar tumor in which the cells have both exocrine and neuroendocrine differentiation, with mucus and neuroendocrine granules within the cytoplasm. In the 2010 WHO classification of tumors of the digestive tract, they have been included in the intermediate-grade malignant category of mixed adenoneuroendocrine carcinomas (MANECs). These tumors are extremely rare in the gastrointestinal tract. Four cases have been reported in the stomach, three in the pancreas, and one in the liver. To the best of our knowledge, this report describes the first case of amphicrine carcinoma in the ampullary region.
Tumori 2015; 101(2): e70 - e72
Article Type: CASE REPORT
AuthorsAlessandro Ginori, Giuseppe Lo Bello, Loretta Vassallo, Sergio Antonio Tripodi
- • Accepted on 30/06/2014
- • Available online on 20/02/2015
- • Published online on 28/04/2015
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- Ginori, Alessandro [PubMed] [Google Scholar] 1, * Corresponding Author (email@example.com)
- Bello, Giuseppe Lo [PubMed] [Google Scholar] 1
- Vassallo, Loretta [PubMed] [Google Scholar] 1
- Tripodi, Sergio Antonio [PubMed] [Google Scholar] 2
Department of Medical Biotechnologies, Pathology Unit, University of Siena, Siena - Italy
Pathology Unit, Azienda Ospedaliera Universitaria Senese, Siena - Italy