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A rare case of male breast cavernous-type angioleiomyoma

Abstract

Cutaneous leiomyomas of the breast are extremely rare, particularly in men. Leiomyomas are categorized into three groups: angioleiomyomas, pilar leiomyomas and genital leiomyomas. Angioleiomyomas, or vascular leiomyomas, are benign tumors arising from smooth muscle cells of arterial or venous walls. We report the case of a 70-year-old man who was admitted to the surgery unit because of a painful lump in the left periareolar region. Ultrasound investigation showed a well-delimited, hyperechogenic, inhomogeneous nodular lesion. The final diagnosis was made after surgical excision and pathological evaluation of the mass. The histological features and immunohistochemical profile, characterized by positive expression of the spindle-shaped tumor cells for desmin and smooth muscle actin and by positive expression of the endothelial cells of the vascular channels for panendothelial markers CD34 and CD31, confirmed the diagnosis of a cavernous-type angioleiomyoma.

Tumori 2014; 100(4): e148 - e152

Article Type: CASE REPORT

DOI:10.1700/1636.17934

Authors

Giovanni Branca, Eleonora Irato, Valeria Barresi, Marialuisa De Marco, Fabio Guccione, Renato Palmeri

Article History

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Authors

  • Branca, Giovanni [PubMed] [Google Scholar]
    Department of Human Pathology, Section of Pathological Anatomy, University of Messina, Messina, Italy
  • Irato, Eleonora [PubMed] [Google Scholar]
    Department of Human Pathology, Section of Pathological Anatomy, University of Messina, Messina, Italy
  • Barresi, Valeria [PubMed] [Google Scholar]
    Department of Human Pathology, Section of Pathological Anatomy, University of Messina, Messina, Italy
  • Marco, Marialuisa De [PubMed] [Google Scholar]
    Department of Human Pathology, Section of Senology, University of Messina, Messina, Italy
  • Guccione, Fabio [PubMed] [Google Scholar]
    Department of Human Pathology, Section of Senology, University of Messina, Messina, Italy
  • Palmeri, Renato [PubMed] [Google Scholar]
    Department of Human Pathology, Section of Senology, University of Messina, Messina, Italy

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