The role of radiation therapy in vulvar cancer: review of the current literature


The purpose of this article is to discuss the current role of radiation therapy in vulvar cancer and especially to review the recent literature relative to the use of intensity-modulated radiotherapy (IMRT) in disease management. Owing to the low incidence of vulvar cancer, at present there are no available results of cooperative prospective trials. As evidenced in dosimetric and preliminary retrospective clinical studies, the use of IMRT has resulted in superior normal tissue sparing and lower rates of acute and chronic toxicities compared to previous studies that used conventional approaches. Data on long-term outcomes in these patients remain limited.

Tumori 2017; 103(5): 422 - 429

Article Type: REVIEW



Piera Sciacero, Domenico Cante, Cristina Piva, Valeria Casanova Borca, Edoardo Petrucci, Luca Gastaldi, Maria Rosa La Porta, Pierfrancesco Franco

Article History


Financial support: None to declare.
Conflict of interest: The authors declare they do not have any conflict of interest.

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  •  Radiotherapy Department, Ivrea Community Hospital, ASL TO4, Ivrea (Turin) - Italy
  •  Medical Physics Department, Ivrea Community Hospital, ASL TO4, Ivrea (Turin) - Italy
  •  Department of Oncology, Radiation Oncology, University of Turin, Turin - Italy

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