Advertisement

Primary bone lymphoma of the talus: a challenging diagnosis

Abstract

Purpose

Diagnostic challenges are common in clinical practice and diagnostic or classification criteria for musculoskeletal conditions cannot overshadow clinical skills.

Methods

We present the case of a young man who complained of prolonged articular pain and mild swelling of the right ankle in the absence of other remarkable data. Apparently fulfilling the Budapest diagnostic criteria for complex regional pain syndrome, the patient was treated accordingly, but the pain increased over time. Then the patient underwent an additional diagnostic workup including synovial and bone biopsies in 2 separate occasions with the second one demonstrating diffuse lymphoid infiltrate compatible with lymphoma.

Results

The conclusive diagnosis of primary diffuse large B-cell lymphoma of the talus was made and adequate treatment initiated.

Conclusions

The diagnostic difficulties as well as the importance of a multidisciplinary approach for complex cases are highlighted in this report.

Tumori 2017; 103(Suppl. 1): e62 - e65

Article Type: CASE REPORT

DOI:10.5301/tj.5000648

Authors

Ombretta Annibali, Gianluigi Fabbriciani, Mariantonietta Tafuri, Marco Massarotti, Pietro Sedati, Valeria Tomarchio, Elena Sabattini, Stefano Pileri, Carlo Selmi, Giuseppe Avvisati

Article History

Disclosures

Financial support: No financial support was received for this submission.
Conflict of interest: None of the authors has conflict of interest with this submission.

This article is available as full text PDF.

  • If you are a Subscriber, please log in now.

  • Article price: Eur 36,00
  • You will be granted access to the article for 72 hours and you will be able to download any format (PDF or ePUB). The article will be available in your login area under "My PayPerView". You will need to register a new account (unless you already own an account with this journal), and you will be guided through our online shop. Online purchases are paid by Credit Card through PayPal.
  • If you are not a Subscriber you may:
  • Subscribe to this journal
  • Unlimited access to all our archives, 24 hour a day, every day of the week.

Authors

Affiliations

  • Hematology and Stem Cell Transplantation Unit, University Campus Bio-Medico, Rome - Italy
  • Reumatology Department, IRCCS Istituto Ortopedico Galeazzi, Milan - Italy
  • Rheumatology and Clinical Immunology Unit, Humanitas Clinical and Research Center, Milan - Italy
  • Department of Rheumatology, University Hospitals of Morecambe Bay NHS Foundation Trust, Royal Lancaster Infirmary, Lancaster - UK
  • Radiology Unit, University Campus Bio-Medico, Rome - Italy
  • Hematopathology Section, Department of Hematology and Oncological Sciences “L. and A. Seràgnoli,” S. Orsola-Malpighi Hospital, University of Bologna, Bologna - Italy
  • Haematopathology Unit, European Institute of Oncology, Milan - Italy
  • BIOMETRA Department, University of Milan, Milan - Italy
  • Ombretta Annibali and Gianluigi Fabbriciani contributed equally to this work.

Article usage statistics

The blue line displays unique views in the time frame indicated.
The yellow line displays unique downloads.
Views and downloads are counted only once per session.

No supplementary material is available for this article.